Commanders vs. 49ers picks and prediction market prices on Polymarket for Monday Night Football

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Washington Commanders quarterback Jayden Daniels (5) runs the ball against the New York Giants during the first half of NFL football game in Landover, Md., Sunday, Oct. 11, 2026. (AP Photo/Stephanie Scarbrough)

Monday Night Football is here, and the October 19 matchup between the Washington Commanders and San Francisco 49ers features two teams heading in completely different directions. San Francisco enters at 5-0, while Washington has struggled to find the momentum that Jayden Daniels originally brought to the organization.

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